Famenity, a research and development corporation that develops natural medicinal products, has launched the MR-10, which is a natural dietary ingredient blend composed of botanical bioactive compounds extracted from Korean dandelion and rooibos.
In a series of published, peer-reviewed in vitro, in vivo, and human clinical studies, researchers found that MR-10 exerted significant improvements in alleviating various male andropause symptoms, up-regulating serum testosterone levels, and increasing sperm count and activity, the company said in a release.
According to the company, in addition to proven efficacy, a suite of toxicology studies were conducted on MR-10 and found that it is a safe, nontoxic ingredient with no adverse effects reported. Androgens are male sex hormones (such as testosterone) and as men age, it is common for androgen levels to progressively decline. Andropause is defined as a collection of symptoms experienced by some middle-aged or elderly men resulting from the gradual decline in testosterone levels over time.
These symptoms can include fatigue, a decrease in libido, loss of skeletal muscle mass, a decrease in energy and physical capacity, minor depression, and decreased sperm motility. Safe, natural substances capable of reducing andropause symptoms in aging men are essential, due to the fact that an increasing proportion of men will become affected as the general life span is prolonged.
MR-10 raw materials
Korean dandelion (Taraxacum platycarpum) is a perennial herbaceous plant and a member of the Asteraceae family. Korean dandelion has been used as a medicinal herbal remedy in ancient traditional Korean medicine for centuries. Rooibos (Aspalathus linearis) is a member of the Leguminosae family native to South Africa. Rooibos, meaning “red bush”, is commonly consumed as a caffeine-free herbal tea.
Characteristics and applications
The bioactive components from the Korean dandelion plant and the fermented leaves of the rooibos plant are purified into a proprietary powdered extract. MR-10 is a free-flowing, reddish-brown powder and is shelf-stable for up to three years when stored at room temperature.
MR-10 is water-soluble and heat-stable and can be used as a formulation ingredient in various dietary supplement applications, the company said. Serving forms include tablets, capsules, gel tabs, gummies, beverages, films, and powdered mixes. The recommended serving size is 400 mg per day, as this was the dose tested in the human clinical trials that resulted in two significant improvements in andropause symptoms as well as a safe serving level established through toxicology testing.